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Through careful, deliberate thought this book provides the nonmathematician with a foundation for understanding the underlying statistical reasoning process in clinical research. This volume recognizes the inevitable tension between the mathematics of hypothesis testing and the ethical requirements in medical research and concentrates on the resolution of these issues in P value interpretation. By presenting the material in a conversational format and consciously de-emphasizing computational devices and focusing instead on the features of experimental design that either clarify or blur P value interpretation statistical reasoning becomes extremely accessible to the uninitiated.
